Emergency (24/7) Plumbing

At low concentrations (sub-micromolar scale), CBD binds to equilibrative nucleoside transporter (ENT), transient receptor potential melastatin type 8 (TRPM8),...

CBD is also an antagonist of the orphan receptor GPR559696.Nonpsychotropic Plant Cannabinoids, Cannabidivarin (CBDV) and Cannabidiol (CBD),...

Therefore, double-blind, placebo-controlled, randomized trials with larger samples of patients with PD are needed to elucidate the possible effectiveness...

Despite the consensus among researchers on the potential of CBD as a neuroprotective agent, larger and well-designed randomized clinical trials...

Besides, several studies have described CBD as a multitarget molecule, acting as an adaptogen and as a modulator, in different...

An open-label pilot study conducted in PD patients showed that oral doses of CBD ranging from 150-400 mg/day, combined...

The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin.Pharmacokinetics, Safety,...

Studies show that CBD can increase AEA concentration by blocking the AEA membrane transporter (AMT) or the...

On the other hand, daily administration of CBD (3 mg/kg) for 14 days decreased both dopamine depletion and tyrosine hydroxylase expression within the striatum of...

increases 2-AG levels,8989.Effects of cannabidiol in the treatment of patients with Parkinson's disease: An exploratory double-blind trial -...